Cytosine modules

1. Caloric restriction is associated with cytosine modules in silico.

   “methylation state of some modules responds to perturbations such as caloric restriction, ablation of growth hormone receptors, consumption of high-fat diets, and expression of Yamanaka factors”

   In silicoin mammalian DNA methylation modules

   DNA methylation networks underlying mammalian traits

   Science (New York, N.Y.)·Aug 10, 2023

More on Caloric restriction

1. Cytosine modules are associated with lifespan in silico.

   “identified 55 distinct cytosine modules, of which 30 are related to traits such as maximum life span, adult weight, age, sex, and human mortality risk”

   In silico

   DNA methylation networks underlying mammalian traits

   Science (New York, N.Y.)·Aug 10, 2023