DNA methylation profiles

1 paper1 finding

In silico1

Associations

1

Age

mixedin humans1

1 study

DNA methylation profiles are associated with age in humans (P<0.0001).
“Methylation profile classes derived from unsupervised modeling were significantly associated with age (P<0.0001)”
Humans
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context
PLoS genetics14 Aug 2009

Latest

15 in 12 months

bioRxiv2 Oct

Early life stress accelerates epigenetic aging in zebra finches

Corticosterone treatment shifts DNA methylation profiles in young chicks toward those of older birds and reshapes longevity pathways.Corticosterone treatment shifts DNA methylation profiles in young chicks toward those of older birds and reshapes longevity pathways.

Preprint: experiments in zebra finchesMechanisms

Research Square24 Sep

Donor Age Impairs Vasculogenic Potential of hiPSC-Derived Endothelial Progenitors via Elevated Mitochondrial Reactive Oxygen Species

Preprint: experiments in human cellsOxidative stress and ROS signalling

American Journal of Hypertension23 Sep

Genome-Wide DNA Methylation Profiling in Patients with Hypertension and Asymptomatic Intracranial Atherosclerotic Stenosis

Cohort study of 281 peopleHypertension

Cardiovascular Diabetology13 Sep

Epigenetic and genetic factors modifying the association between diet quality and incident type 2 diabetes: the EPIC-Potsdam cohort

Cohort study of 2,204 peopleType 2 diabetes

Experimental Gerontology9 Sep

Epigenetic aging and autosomal methylation remodeling in Anderson-Fabry disease

Cross-sectional study of 32 peopleBiomarkers

Biology Letters8 Sep

DNA methylation-based ageing in a deuterostome invertebrate: an epigenetic clock for the crown-of-thorns seastar (Acanthaster cf. solaris)

Experiments in model organismsEpigenetic clock

Nature Communications30 Aug

Associations between diet quality, epigenetic aging and epigenome in two population-based cohorts

Cohort study in peoplePopulations

bioRxiv29 Aug

Early-Life Wildfire Smoke Exposure Is Associated with Long-Term Systemic Immune Remodeling and Epigenetic Reprogramming

Preprint: experiments in monkeysImmune response

bioRxiv29 Aug

MOSurvivor-Guided Joint CpG Selection and XGBoost Hyperparameter Optimization for Compact Epigenetic Age Prediction

Preprint: computational studyBiomarkers

bioRxiv24 Aug

Replicative history as a major determinant of epigenetic noise across human tissues

Preprint: cohort study of 1,531 peopleMechanisms