Cxcl1, Il6, and Adam8 gene expression

1. ADAM8 decreases Cxcl1, Il6, and Adam8 gene expression in mice.

   “Cxcl1, Il6, and Adam8 gene expression levels were higher in the injured tail IVDs of 3-month-old Adam8EQ than WT mice (n = 18-30; p < 0.05)”

   Animalsshown by higher expression in Adam8EQ inactivation mutants than wild-type mice after injurytail intervertebral disc1 week post injury

   Effects of Age on Intervertebral Disc Tissue Morphology and Gene Expression in the ADAM8-Inactivation Mouse

   Cells·20 Apr 2026

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