CSF biomarkers
Biomarker1 paper
- Humans1
Funding
National Institute on AgingUS$798.3k1 grant since 2021
Latest
62Spinal fluid protein linked to Alzheimer’s dementia risk
An observational study of 444 people without dementia linked a blood vessel-related protein to poorer thinking, brain shrinkage and later Alzheimer’s…An observational study of 444 people without dementia linked a blood vessel-related protein to poorer thinking, brain shrinkage and later Alzheimer’s dementia.
High neutrophil-to-lymphocyte ratio predicts cognitive decline
During five years of follow-up, 42.55% of older adults with high ratios progressed to mild cognitive impairment or dementia compared with 30.82% with…During five years of follow-up, 42.55% of older adults with high ratios progressed to mild cognitive impairment or dementia compared with 30.82% with normal ratios.
GLP-1 receptor agonists link to lower stroke and Alzheimer risk
A cross-ancestry Mendelian randomization study of up to 1,812,017 individuals linked genetically proxied GLP-1 receptor agonist exposure to reduced…A cross-ancestry Mendelian randomization study of up to 1,812,017 individuals linked genetically proxied GLP-1 receptor agonist exposure to reduced risk of stroke and Alzheimer disease.
Social isolation links to amyloid pathology and lower cognition
In 957 non-demented adults, social isolation was associated with lower cognitive scores, decreased cerebrospinal fluid amyloid-beta levels, and higher…In 957 non-demented adults, social isolation was associated with lower cognitive scores, decreased cerebrospinal fluid amyloid-beta levels, and higher tau-to-amyloid ratios.