Cortical amyloid SUVR

1. Locus coeruleus contrast-to-noise ratio is associated with cortical amyloid SUVR in humans.

   “We observed negative associations between LC integrity and amyloid SUVR across almost all cortical regions”

   Humansasymptomatic, at-risk older adults with first-degree familial history of Alzheimer's diseasebrainn = 208

   Locus coeruleus structural integrity relates to cortical amyloid and tau pathology in vivo

   AAIC 2025 abstract·23 Dec 2025

More on Locus coeruleus contrast-to-noise ratio

1. Locus coeruleus structural integrity is associated with cortical amyloid SUVR in humans.

   “We observed negative associations between LC integrity and amyloid SUVR across almost all cortical regions”

   Humansasymptomatic, at-risk older adults with first-degree familial history of Alzheimer's diseasebrainn = 208

   Locus coeruleus structural integrity relates to cortical amyloid and tau pathology in vivo

   AAIC 2025 abstract·23 Dec 2025