Copeptin

1. Dapagliflozin increases copeptin in humans (7.8 pmol/L (95% CI: 2.77-12.81)).

   “Dapagliflozin treatment increased serum copeptin early (5.5 pmol/L [95% CI: 0.45-10.5]; P < 0.05) and late (7.8 pmol/L [95% CI: 2.77-12.81]; P < 0.01)”

   Human trialheart failure with reduced ejection fraction10 mg daily4 weeksn = 29

   Water Conservation Overrides Osmotic Diuresis During SGLT2 Inhibition in Patients With Heart Failure

   Journal of the American College of Cardiology·Apr 11, 2024

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