Urine glucose excretion

1. Dapagliflozin increases urine glucose excretion in humans (2.7 mmol/kg/d (95% CI: 1.98-3.51)).

   “Dapagliflozin treatment led to an isolated increase in urine glucose excretion by 3.3 mmol/kg/d (95% CI: 2.51-4.04; P < 0.0001) within 48 hours (early) which persisted after 4 weeks”

   Human trialheart failure with reduced ejection fraction10 mg daily4 weeksn = 29

   Water Conservation Overrides Osmotic Diuresis During SGLT2 Inhibition in Patients With Heart Failure

   Journal of the American College of Cardiology·Apr 11, 2024

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