COL1 protein abundance

1. Aerobic exercise has no effect on COL1 protein abundance in humans.

   “mixed-effects analysis revealed no significant main effects of group or time and no group × time interactions for COL1, COL3, SMAD, pSMAD, or TGFB1 protein abundance.”

   Human trialtype 2 diabetesskeletal muscle12-wks

   Aerobic Exercise Modulates Fibrotic Signaling without Excess Collagen Accumulation in Skeletal Muscle of Adults with Type 2 Diabetes

   ADA Scientific Sessions 2026 abstract·5 Jun 2026

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