Circulating small extracellular vesicle-derived miRNAs

1. Chronic kidney disease decreases circulating small extracellular vesicle-derived miRNAs in humans.

   “Twenty-three miRNAs were significantly downregulated in advanced CKD, associated with cellular senescence, FOXO (forkhead box, class O) signaling, and cell cycle pathways.”

   Humansin patients with CKD

   Circulating Extracellular Vesicle MicroRNAs as Predictive Biomarkers for Kidney and Cardiovascular Events

   Journal of the American Heart Association·10 Dec 2025

More on Chronic kidney disease

1. Circulating small extracellular vesicle-derived miRNAs is associated with cardiorenal anemia syndrome in humans.

   “Lower miRNA levels were linked to cardiovascular comorbidities and cardiorenal anemia syndrome.”

   Humansin patients with CKD

   Circulating Extracellular Vesicle MicroRNAs as Predictive Biomarkers for Kidney and Cardiovascular Events

   Journal of the American Heart Association·10 Dec 2025

More on Cardiorenal anemia syndrome

1. Circulating small extracellular vesicle-derived miRNAs is associated with cardiovascular comorbidities in humans.

   “Lower miRNA levels were linked to cardiovascular comorbidities and cardiorenal anemia syndrome.”

   Humansin patients with CKD

   Circulating Extracellular Vesicle MicroRNAs as Predictive Biomarkers for Kidney and Cardiovascular Events

   Journal of the American Heart Association·10 Dec 2025

More on Cardiovascular comorbidities