Circulating PCSK9
1 paper1 finding
Interventions
1PCSK9 base editing
downin reviews1
1 study
PCSK9 base editing
downin reviews1
PCSK9 base editing decreases circulating PCSK9.
“Preliminary interim and preclinical data suggest that this strategy is effective for long-term reduction of PCSK9 and LDL-C following a single IV infusion.”
Reviewpreliminary interim and preclinical datapackaged within lipid nanoparticlessingle IV infusion
In-vivo CRISPR/Base-Editing "One-Shot" Therapies Targeting PCSK9
Current atherosclerosis reportsOct 15, 2026
Latest
5 in 12 monthsCurrent Atherosclerosis Reports
In-vivo CRISPR/Base-Editing "One-Shot" Therapies Targeting PCSK9
ReviewInterventions
American Journal of Preventive Cardiology
Circulating PCSK9 as a sex-stratified predictor in primary prevention of cardiovascular disease: Insights from a prospective cohort study in Chinese adults
Cohort study of 1,876 peopleCardiovascular disease
Oncology Letters
Circulating PCSK9: A new frontier in cancer risk stratification for obese diabetics
Cohort study of 141 peopleCancer
Drug Discoveries & Therapeutics
Enlicitide: The first oral PCSK9 inhibitor approved for treatment of hypercholesterolemia
Trial in peopleEnlicitide
The American Journal of Medicine
Association between PCSK9 targeted therapy and the risk of stroke and dementia: A meta-analysis of randomized controlled trials
Meta-analysis of randomized trialsDementia
Journal of Lipid Research
Influence of physiological changes in endogenous estrogen on circulating PCSK9 and LDL cholesterol
Cross-sectional study of 206 peopleMechanisms