CGRP+ nerve fiber density

Older age is associated with CGRP+ nerve fiber density in mice.

“Nociceptive CGRP+ nerve fiber density was also elevated in aged males, whereas sympathetic TH+ fiber density remained unchanged across age and sex groups.”

Animalsanterior knee jointmales

3D Light sheet microscopy reveals aging osteoarthritis-associated joint-innervated nerve remodeling in mouse knee joints

Osteoarthritis and cartilage·23 Apr 2026