Cerebrovascular response to exercise

1. Cerebrovascular response to exercise was not clearly linked with dual task interference in non-carriers of APOE4 (p > 0.187).

   “no relationships were observed in non-carriers (p > 0.187)”

   Humansin non-carriers of APOE4n = 22

   APOE4 carriers resistant to cognitive decline show unique relationships between cerebrovascular response to exercise and dual-task cognitive-balance performance

   Frontiers in neuroscience·Apr 13, 2026

1. Cerebrovascular response to exercise is linked with better response inhibition in APOE4 carriers with greater Aβ deposition.

   “Despite having greater Aβ deposition, APOE4 carriers with higher CVR demonstrated better response inhibition.”

   Humansin APOE4 carriers with greater Aβ deposition

   Cerebrovascular response to exercise interacts with individual genotype and amyloid-beta deposition to influence response inhibition with aging

   Neurobiology of aging·Mar 4, 2022

1. Cerebrovascular response to exercise is associated with cognitive dual-task interference in APOE4 carriers (r = 0.832, p = 0.020).

   “less cognitive DTI (r = 0.832, p = 0.020)”

   Humansin APOE4 carriersn = 8

   APOE4 carriers resistant to cognitive decline show unique relationships between cerebrovascular response to exercise and dual-task cognitive-balance performance

   Frontiers in neuroscience·Apr 13, 2026

1. Cerebrovascular response to exercise is associated with balance dual-task interference in APOE4 carriers (r = 0.839, p = 0.009).

   “higher cerebrovascular response to exercise was associated with less balance DTI (r = 0.839, p = 0.009)”

   Humansin APOE4 carriersn = 8

   APOE4 carriers resistant to cognitive decline show unique relationships between cerebrovascular response to exercise and dual-task cognitive-balance performance

   Frontiers in neuroscience·Apr 13, 2026

1. Cerebrovascular response to exercise is associated with response inhibition in APOE4 carriers.

   “Blunted CVR was associated with impaired response inhibition specifically in APOE4 carriers.”

   Humansin APOE4 carriers

   Cerebrovascular response to exercise interacts with individual genotype and amyloid-beta deposition to influence response inhibition with aging

   Neurobiology of aging·Mar 4, 2022

1. Cerebrovascular response to exercise is associated with amyloid-beta deposition in cognitively normal older adults.

   “Individuals with blunted CVR possessed greater Aβ deposition.”

   Humansin cognitively normal older adults

   Cerebrovascular response to exercise interacts with individual genotype and amyloid-beta deposition to influence response inhibition with aging

   Neurobiology of aging·Mar 4, 2022

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