CD8+ HLA-DRB1+ T cells

1. Systemic lupus erythematosus increases CD8+ HLA-DRB1+ T cells in humans.

   “CD8+ HLA-DRB1+ T cells were enriched within effector memory and terminally differentiated CD8+ T cells and were significantly expanded within the effector memory compartment in SLE”

   Humansin systemic lupus erythematosus

   Type I interferon drives dysfunction of a distinct CD8+ HLA-DRB1+ T cell subset in systemic lupus erythematosus

   medRxiv : the preprint server for health sciences·3 Jan 2026Preprint

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