Causal aging-associated loci

1. Liver-unique methylation sites are associated with causal aging-associated loci in silico.

   “we identify significant enrichment of liver-unique methylation sites in causal aging-associated loci, particularly sites that are highly methylated in healthy liver.”

   In silicoparticularly sites highly methylated in healthy liverliver

   Reversible and causal epigenetic information loss in liver aging and disease

   PNAS nexus·10 Apr 2026

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