Cardiovascular disease risk score

Biomarker

3 papers2 findings

  • Humans3

Effects

2

Attentional orienting

downin humans1

1 study
  1. Cardiovascular disease risk score impairs attentional orienting in humans.

    “in men, greater CVD risk score was associated with worse attentional orienting only in those with worst global sleep quality (PSQI-Total ∼11; p=.02)”

    Humansworst global sleep quality (PSQI-Total ∼11)males

    The Sleep-Heart-Brain Connection: Sex-Specific Modifiable Risk Factors and Cognitive Impact in Mid-to-Late Life

    GSA 2025 abstract31 Dec 2025

Total brain tissue volume

mediatesin humans1

1 study
  1. Cardiovascular disease risk score mediates total brain tissue volume in humans.

    “Cardiovascular risk score, examined in a subsample of 893 participants, mediated this association for total brain tissue but not for hippocampal volume.”

    Humansassociation between neighborhood disadvantage and total brain tissue volumen = 893

    Association of Neighborhood-Level Disadvantage With Cerebral and Hippocampal Volume

    JAMA neurology1 Apr 2020

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