What does the research say about buckling ratio?

Buckling ratio

There are 10 papers on buckling ratio in aging research: 1 trial and 9 observational studies in people. The newest story, Oct 25, 2026: “Hip analysis assumption linked to errors in donated human bones”.

Biomarker

10 papers study it15 more mention it3 findings

2 new papers in 30 daysSee all 25 papers on buckling ratio

“Higher S endocortical diameter (1.81, 1.29-2.53), and buckling ratio (BR) at all sites (NN: 1.07, 1.04-1.11; IT: 1.08, 1.05-1.11, S: 1.31, 1.19-1.46) were associated with increased risk.”

Hip structure and incident fracture: a time-updating survival analysis over 20 years of data from the Geelong Osteoporosis StudyArchives of osteoporosis2024doi:10.1007/s11657-024-01471-7

Human trial1
Humans9

Upstream

Changsha-Chinese ethnicity

upin humans1

1 study

Changsha-Chinese ethnicity is linked with higher buckling ratio in humans.
“However, their buckling ratio (BR) reference curve was significantly higher than that of the NHWs, NHBs, and Mexican women in the US.”
Humansfemurfemales
Comparisons of reference curves for femoral neck geometric parameters between Changsha-Chinese women and women of three ethnic groups in the United States
Archives of osteoporosisJul 8, 2025

Associations

Visceral adipose tissue

downin humans1

1 study

Visceral adipose tissue predicts buckling ratio in autoimmune diabetes.
“Visceral adipose tissue emerged as a negative independent predictor of BR at IT and NN.”
Humansin autoimmune diabetes
Fat Mass Influences Femur Bone Strength and Geometry Parameters, but Not Bone Mineral Density, in Autoimmune Diabetes: A Pilot Study
Diabetes/metabolism research and reviewsMar 1, 2026

Bone fracture

upin humans1HR 1.31

1 study

Buckling ratio is linked with a higher risk of bone fracture in humans (HR 1.31, 95% CI 1.19-1.46).
“Higher S endocortical diameter (1.81, 1.29-2.53), and buckling ratio (BR) at all sites (NN: 1.07, 1.04-1.11; IT: 1.08, 1.05-1.11, S: 1.31, 1.19-1.46) were associated with increased risk.”
Humansfemalesn = 986
Hip structure and incident fracture: a time-updating survival analysis over 20 years of data from the Geelong Osteoporosis Study
Archives of osteoporosisNov 7, 2024

Latest

3 papers in 12 months

Frontiers in EndocrinologyOct 25

Hip analysis assumption linked to errors in donated human bones

In younger donors, estimates of dense outer bone area had errors up to 36% compared with high-resolution scans when analysis assumed a fixed bone share.In younger donors, estimates of dense outer bone area had errors up to 36% compared with high-resolution scans when analysis assumed a fixed bone share.

Cross-sectional studyBiomarkers