Brain parenchymal fraction

1. DTI-ALPS index is associated with brain parenchymal fraction in humans (β=0.786, p <0.001).

   “however in the MCI cohort the mean DTI‐ALPS index was strongly associated with BPF (β=0.786, p <0.001).”

   Humansin individuals with mild cognitive impairment

   Glymphatic perivascular clearance and extracellular vesicles: neuroimaging & blood‐based biomarkers in mild cognitive impairment

   AAIC 2025 abstract·24 Dec 2025

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