Glymphatic perivascular clearance and extracellular vesicles: neuroimaging & blood‐based biomarkers in mild cognitive impairment

Abstract

Background: Poor glymphatic clearance is associated with various neurodegenerative disorders. Diffusion tensor imaging analysis along the perivascular space (DTI‐ALPS) has been suggested as a non‐invasive technique to assess glymphatic function, with lower DTI‐ALPS indices having been linked to reduced glymphatic function.