Brain–heart interactions

1. Brain–heart interactions are associated with freezing of gait in humans.

   “the analysis of FOG episodes revealed the emergence of specific BHI interaction clusters preceding and during gait freezing”

   HumansParkinson’s disease; preceding and during freezing episodes

   Assessing ageing, cognitive ability and freezing of gait in Parkinson’s disease through integrated brain–heart network dynamics

   medRxiv·23 Apr 2026Preprint

More on Freezing of gait

1. Brain–heart interactions are associated with cognitive function in humans.

   “resting-state BHI metrics were associated with cognitive performance in early PD”

   Humansearly-stage Parkinson’s disease; resting state

   Assessing ageing, cognitive ability and freezing of gait in Parkinson’s disease through integrated brain–heart network dynamics

   medRxiv·23 Apr 2026Preprint

1. Brain–heart interactions are associated with age and Parkinson’s disease group in humans.

   “we observed distinct BHI profiles differentiating Healthy Young, Healthy Elderly, and PD participants”

   Humanshealthy young adults, healthy elderly participants, and early-stage Parkinson’s disease patients at rest

   Assessing ageing, cognitive ability and freezing of gait in Parkinson’s disease through integrated brain–heart network dynamics

   medRxiv·23 Apr 2026Preprint