Brain glucose metabolism

Biomarker

4 papers1 finding

  • Human trial1
  • Humans3

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APOE

downin humans1

1 study
  1. APOE decreases brain glucose metabolism in humans.

    “They had significantly reduced rates of glucose metabolism in the same posterior cingulate, parietal, temporal, and prefrontal regions as in previously studied patients with probable Alzheimer's disease.”

    Humanscognitively normal, family history of probable Alzheimer's diseasebrain

    Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E

    The New England journal of medicine21 Mar 1996

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