Braak NFT stage

1. flortaucipir-PET is associated with Braak NFT stage in humans (ρ=0.76, p = 0.017).

   “After removing the aforementioned outliers, whole temporal and NEO‐T SUVR correlated significantly with B score (both ρ=0.76, p = 0.017, n = 9).”

   Humansafter removing outliersbrainn = 9

   Preliminary autopsy findings from the Harvard Aging Brain Study

   AAIC 2025 abstract·26 Dec 2025

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1. Braak NFT stage raises the risk of dementia in humans (β=1.9 [1.2 – 2.9]).

   “The development model identified strong total pathological contributions from NFT stage (β=1.9 [1.2 – 2.9])”

   Humansbrain

   Estimating the total burden of multiple neuropathological changes

   AAIC 2025 abstract·23 Dec 2025

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