Biphasic rest-activity instability

Biomarker

1 paper1 finding

  • Humans1

Associations

1

Accelerated biological aging

upin humans1

1 study
  1. Biphasic rest-activity instability is associated with accelerated biological aging in humans.

    “males exhibited a biphasic instability phenotype, characterized by early-morning surges and late-evening rebounds, uniquely linked to accelerated aging.”

    HumansEarly-morning surges and late-evening reboundsMulti-yearMales

    Digital Phenotyping of Rest-Activity Rhythms and Biological Aging from Longitudinal Monitoring with Commercial Wearable Devices in All of Us

    medRxiv29 Sep 2025Preprint

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