Average ganglion cell layer thickness

1. Insulin resistance is associated with average ganglion cell layer thickness in humans (β = -0.062, 95% CI -0.125 to 0.001; FDR-adjusted p = 0.096).

   “was no longer significant in the fully adjusted model (β = -0.062, 95% CI: -0.125 to 0.001; FDR-adjusted p = 0.096).”

   HumansHOMA-IR-defined insulin resistance; fully adjusted model with false discovery rate correctionretinal ganglion cell layern = 6,941

   Impact of Insulin Resistance on Retinal Ganglion Cell Layer Structures: Findings from the Korea National Health and Nutrition Examination Survey

   Journal of clinical medicine·28 Sep 2026

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1. Hyperinsulinaemia is associated with average ganglion cell layer thickness in humans (β = -0.106, 95% CI -0.179 to -0.032).

   “hyperinsulinaemia was significantly associated with a reduced average GCL thickness after full adjustment”

   HumansFully adjusted model with false discovery rate correctionretinal ganglion cell layern = 6,941

   Impact of Insulin Resistance on Retinal Ganglion Cell Layer Structures: Findings from the Korea National Health and Nutrition Examination Survey

   Journal of clinical medicine·28 Sep 2026

More on Hyperinsulinaemia