Autosomal mosaic chromosomal alterations

Biomarker

1 paper1 finding

Humans1

Associations

Suicide death

upin humans1OR 1.78

1 study

Autosomal mosaic chromosomal alterations are associated with suicide death in humans (OR 1.78).
“Total mCAs in autosomal chromosomes were significantly increased in suicide (p = 1.28 × 10−6, odds ratio [OR] = 1.78)”
Humansblood
Increased somatic mosaicism in autosomal and X chromosomes for suicide death
Molecular psychiatry30 Aug 2024

Latest

1 in 12 months

medRxiv2 Oct

Clonal hematopoiesis is linked to frailty in human cohorts

An analysis of 730,088 participants across four cohorts found clonal hematopoiesis was strongly associated with incident frailty and faster functional decline.An analysis of 730,088 participants across four cohorts found clonal hematopoiesis was strongly associated with incident frailty and faster functional decline.

Preprint: cohort study of 730,088 peopleBlood and immune system

Paper

Molecular Psychiatry31 Aug

Increased somatic mosaicism in autosomal and X chromosomes for suicide death

Study of 177,740 peopleMechanisms