Atypical white matter glucose metabolism

Atypical white matter glucose metabolism predicts cognitive decline in humans.

“higher EWM and lower AWM metabolism predicted slower cognitive decline”

Humansatypical white matter

Divergent white matter metabolic signature patterns indicate impending cognitive decline in aging and dementia

Nature communications·19 Mar 2026

Atypical white matter glucose metabolism is associated with cognitive function in humans.

“increased metabolism in atypical WM (AWM; corona radiata) was linked to worse cognition”

Humansatypical white matter

Divergent white matter metabolic signature patterns indicate impending cognitive decline in aging and dementia

Nature communications·19 Mar 2026