Atrophy-related gene expression

Biomarker

1 paper2 findings

  • Cells1

Interventions

2

Gastric inhibitory polypeptide

no changein human cells1

1 study
  1. Gastric inhibitory polypeptide has no effect on atrophy-related gene expression in human cells.

    “Neither semaglutide nor GIP altered atrophy-related gene expression or the secretome, with no proteins reaching significance.”

    Cellsin primary human myotubesskeletal muscle

    GLP-1 and GIP receptor agonism does not directly drive skeletal muscle atrophy or impair myogenesis in primary human myotubes

    bioRxiv (Cold Spring Harbor Laboratory)23 Jul 2026Preprint

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Semaglutide

no changein human cells1

1 study
  1. Semaglutide has no effect on atrophy-related gene expression in human cells.

    “Neither semaglutide nor GIP altered atrophy-related gene expression or the secretome, with no proteins reaching significance.”

    Cellsin primary human myotubesskeletal muscle

    GLP-1 and GIP receptor agonism does not directly drive skeletal muscle atrophy or impair myogenesis in primary human myotubes

    bioRxiv (Cold Spring Harbor Laboratory)23 Jul 2026Preprint

More on Semaglutide

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