In a brain-imaging experiment, memory-related activity reductions in several regions did not differ between younger and older adults completing an object-categorisation…In a brain-imaging experiment, memory-related activity reductions in several regions did not differ between younger and older adults completing an object-categorisation task.
Preprint: cross-sectional study in peopleMechanisms
An observational study of 353 adults aged 36–87 linked distinct brain patterns to later depression in younger women and blood markers of brain deterioration in older men.An observational study of 353 adults aged 36–87 linked distinct brain patterns to later depression in younger women and blood markers of brain deterioration in older men.
In a study of App SAA knock-in mice from 4 to 19 months, animals developed progressive amyloid pathology, neuroinflammation, biomarker shifts, and synaptic loss.In a study of App SAA knock-in mice from 4 to 19 months, animals developed progressive amyloid pathology, neuroinflammation, biomarker shifts, and synaptic loss.