Theranostics
Removing a gene reduced age-related bone loss in mice
In experiments with 12 mice per group, deleting the gene in bone-building cells reduced bone loss after 12 weeks of chemically induced aging.In experiments with 12 mice per group, deleting the gene in bone-building cells reduced bone loss after 12 weeks of chemically induced aging.
Mouse studyBones and joints
Who was studiedMale mice with D-galactose-induced aging, against D-gal-treated wild-type mice
What changedBone density was higher in mice lacking ARG2 in bone-forming cells than in D-galactose-treated mice with the gene intact
The catchGene-deletion experiments measured chemically induced bone loss, not bone loss during natural aging