Aqp2 abundance

Older age and past pregnancy is associated with Aqp2 abundance in rats.

“Twelve month versus 4.5 month females exhibited ~25% higher GFR, lower abundance of key Na+ transporters, higher AQP2 abundance, and comparable urinary excretion rates.”

Animals12-month breeders compared with 4.5-month virginsrenal tubulefemales

Age-Related Adaptations in Renal Tubular Function in Female Rats

Acta physiologica (Oxford, England)·18 Apr 2026