Amyloid, tau, or neurodegeneration biomarker trajectories

Premorbid intellectual impairment has no effect on amyloid, tau, or neurodegeneration biomarker trajectories in humans.

“Differences in PII did not significantly affect amyloid, tau, or neurodegeneration biomarker trajectories.”

Humansin Down syndrome associated Alzheimer's disease

Mild premorbid intellectual impairment as a resilience factor in Down syndrome associated Alzheimer's disease

AAIC 2025 abstract·24 Dec 2025