Amyloid-beta PET centiloid

Amyloid-beta PET centiloid increases white matter hyperintensities growth rate in humans.

“Growth rates of WMH increased with baseline beta‐amyloid burden ( p <0.05)”

Humansabove and beyond age, sex, and APOE4 statuswhite mattern = 1,245

Differences in growth rates and spatial patterns of white matter hyperintensities between beta‐amyloid burden and vascular risk

AAIC 2025 abstract·7 Jan 2026

Amyloid-beta PET centiloid is associated with parietal white matter hyperintensities growth in humans.

“Longitudinally, the association for beta‐amyloid burden ( p <0.005) persisted in only the parietal WMH”

Humansparietal white mattern = 1,245

Differences in growth rates and spatial patterns of white matter hyperintensities between beta‐amyloid burden and vascular risk

AAIC 2025 abstract·7 Jan 2026

Age is associated with amyloid-beta PET centiloid in humans.

“Aβ values increased with age in the upper percentiles for both Koreans and NHWs.”

Humansin upper percentiles

Age‐related amyloid‐β dynamics modeled with the generalized additive model for location, scale, and shape (GAMLSS) across diverse populations: cross‐sectional trajectories and longitudinal validation

AAIC 2025 abstract·7 Jan 2026