Allopregnanolone
3 papers study it10 more mention it1 finding
- Humans1
- Animals1
Associations
1Age
mixedin humans1
1 study
Age
mixedin humans1
Age is associated with allopregnanolone in humans.
“Application of the method showed sex and age effects across the lifespan for both allopregnanolone and testosterone”
Humansserum
Scientific reportsNov 13, 2024
Funding
2 grants since 2018National Institute of Mental HealthUS$947.8kNational Institute on AgingUS$239.3k
Latest
1 paper in 12 monthsNederlands Tijdschrift Voor Geneeskunde
Fluctuating hormones, fluctuating mood? Depression in perimenopause
ReviewMechanisms
Scientific Reports
Age and sex effects of a validated LC-MS/MS method for the simultaneous quantification of testosterone, allopregnanolone, and its isomers in human serum
Cross-sectional study in peopleTestosterone
Pharmacology, Biochemistry, and Behavior
Interaction of age and sex as factors in understanding the anxiolytic effects of alcohol: Unasked questions limiting the understanding of a critical health issue
CommentaryMechanisms
Pharmacology, Biochemistry, and Behavior
Increased anxiolytic effect in aged female rats and increased motoric behavior in aged male rats to acute alcohol administration: Comparison to younger animals
Experiments in ratsMechanisms
Frontiers in Behavioral Neuroscience
GABA System Modifications During Periods of Hormonal Flux Across the Female Lifespan
ReviewMechanisms
Journal of Nutrition and Metabolism
The Aging GABAergic System and Its Nutritional Support
ReviewMechanisms
Journal of Lipid Research
Interleukin 6 reduces allopregnanolone synthesis in the brain and contributes to age-related cognitive decline in mice
Experiments in animalsMechanisms
Journal of Pharmacological Sciences
Role of neurosteroid allopregnanolone on age-related differences in exercise-induced hypoalgesia in rats
Experiments in animalsInterventions
Translational Stroke Research
The 5α-Reductase Inhibitor Finasteride Exerts Neuroprotection Against Ischemic Brain Injury in Aged Male Rats
Experiments in animalsInterventions