AI-ECG delta age

Biomarker

2 papers3 findings

  • Humans2

Associations

3

Adverse vascular events

upin humans1

1 study
  1. AI-ECG delta age predicts adverse vascular events in humans (aHR 1.16 (95% CI 1.12 to 1.21) per 10-year increase).

    “as was a larger delta age (aHR:1.16 [1.12 to 1.21] for every 10-year increase in delta age).”

    Humanspatients with migrainefor every 10-year increase in delta agemedian follow-up time was 54 monthsn = 29,928

    Higher artificial intelligence-ECG atrial fibrillation prediction model output and estimated physiologic aging predict higher risk of adverse vascular events in patients with migraine

    Headache20 Feb 2026

Survival

downin humans1

1 study
  1. AI-ECG delta age predicts survival in humans (time ratio: 0.62, P = 0.017).

    “δage >5.1 years portended shorter survival than a δage between -5.1 and 5.1 years (time ratio: 0.62; P = 0.017).”

    Humanspost cardiac resynchronization therapy with defibrillator, δage >5.1 years vs -5.1 to 5.1 yearsn = 464

    Preimplantation AI-ECG Age as a Predictor of Survival Following Cardiac Resynchronization Therapy

    JACC. Clinical electrophysiology24 Dec 2025

Mortality

downin humans1

1 study
  1. AI-ECG delta age predicts mortality in humans (time ratio: 0.96, P = 0.007).

    “a lower δage correlated with longer survival post implantation (time ratio: 0.96; P = 0.007).”

    Humanspost cardiac resynchronization therapy with defibrillatorn = 464

    Preimplantation AI-ECG Age as a Predictor of Survival Following Cardiac Resynchronization Therapy

    JACC. Clinical electrophysiology24 Dec 2025

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