Aging Proteins

Biomarker

1 paper2 findings

  • Humans1

Associations

2

Biological aging

mixedin humans1

1 study
  1. biological aging is associated with Aging Proteins in humans (311 proteins).

    “311 proteins were differentially expressed across both chronological age and disease burden comparisons and were defined as biological Aging Proteins (APs).”

    Humansplasma

    Plasma Proteomic Profiling of Young and Older Adults Identifies Candidate Biomarkers of Biological Aging at the Intersection of Age and Disease

    Aging cellApr 1, 2026

Chronological age

upin humans1

1 study
  1. Aging Proteins predict chronological age in humans.

    “Plasma levels of APs can predict chronological age”

    Humansplasma

    Markers of aging: Unsupervised integrated analyses of the human plasma proteome

    Frontiers in agingFeb 22, 2023

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bioRxiv

Translation error rates rise with age in post-mitotic mouse cells

Mass spectrometry showed error frequencies increased in post-mitotic mouse tissues during aging but not in dividing cells, correlating with changes in tRNA pools.Mass spectrometry showed error frequencies increased in post-mitotic mouse tissues during aging but not in dividing cells, correlating with changes in tRNA pools.

Preprint: experiments in miceMechanisms