Age-related differentially methylated regions

1. Ultra-conserved CpGs is associated with age-related differentially methylated regions in silico.

   “ucCpGs also strongly co-located within ageing-related Differentially Methylated Regions (age-DMRs), highlighting Clustered Protocadherin Gamma, as well as HSPA2 and LHFPL4 genes.”

   In silico

   Conserved Human CpG Dinucleotides Identify Enriched Ageing-related Signals in Developmental Pathways and the Brain

   bioRxiv (Cold Spring Harbor Laboratory)·20 Feb 2026Preprint

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