Age-associated DNA methylation changes

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Microglial depletion and repopulation

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1 study

Microglial depletion and repopulation decreases age-associated DNA methylation changes in mice.
“microglial repopulation also reversed a large fraction of age-associated DNA methylation changes”
Animalsmicroglia
Microglial Replacement Reverses Age-Associated Epigenetic Modifications Despite Accelerating Epigenetic Age
Aging and disease11 Oct 2025

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Aging and Disease24 Oct

Microglial Replacement Reverses Age-Associated Epigenetic Modifications Despite Accelerating Epigenetic Age

Experiments in miceInterventions