Age-associated differentially methylated positions

Chronological age is associated with age-associated differentially methylated positions in humans (68,630 aDMPs (10%)).

“Across tissues, we identified 68,630 aDMPs (10%) robustly associated with ageing.”

Humanseight human tissuesmale and femalesn = 36,000

Tissue-specific divergence in sex-biased DNA methylation across the lifespan

bioRxiv (Cold Spring Harbor Laboratory)·21 Apr 2026Preprint