Accelerated biological aging
Biomarker1 paper2 findings
- Humans1
Associations
2Early-onset colon adenocarcinoma
upin humans1HR 2.32
1 study
Early-onset colon adenocarcinoma
upin humans1HR 2.32
Accelerated biological aging is associated with early-onset colon adenocarcinoma in humans (HR 2.32, 95% CI 1.38–3.89).
HumansKorean adults; biological age greater than chronological ageMedian follow-up of 7.7 yearsn = 198,491
Faster biological aging linked to early colorectal adenocarcinoma · Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 5 Oct 2026
Early-onset colorectal adenocarcinoma
upin humans1HR 1.93
1 study
Early-onset colorectal adenocarcinoma
upin humans1HR 1.93
Accelerated biological aging is associated with early-onset colorectal adenocarcinoma in humans (HR 1.93, 95% CI 1.28–2.91).
HumansKorean adults; biological age greater than chronological ageMedian follow-up of 7.7 yearsn = 198,491
Faster biological aging linked to early colorectal adenocarcinoma · Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 5 Oct 2026
Latest
10Faster biological aging linked to early colorectal adenocarcinoma
In Korean adults under 50, risk of early-onset colorectal adenocarcinoma was 93% higher in those with accelerated biological aging than in those…In Korean adults under 50, risk of early-onset colorectal adenocarcinoma was 93% higher in those with accelerated biological aging than in those without it.
Benzene exposure links to higher thyroid dysfunction risk
Each 1 μg/m³ increase in ambient benzene was linked to hazard ratios of 1.19 for hypothyroidism and 1.21 for hyperthyroidism.Each 1 μg/m³ increase in ambient benzene was linked to hazard ratios of 1.19 for hypothyroidism and 1.21 for hyperthyroidism.
Clonal hematopoiesis is linked to frailty in human cohorts
An analysis of 730,088 participants across four cohorts found clonal hematopoiesis was strongly associated with incident frailty and faster functional…An analysis of 730,088 participants across four cohorts found clonal hematopoiesis was strongly associated with incident frailty and faster functional decline.
Epigenetic puberty index tracks biological aging and adult health risks
A DNA-methylation measure of pubertal development correlates with established epigenetic clocks and predicts mortality and disease in two large adult…A DNA-methylation measure of pubertal development correlates with established epigenetic clocks and predicts mortality and disease in two large adult cohorts.
Accelerated biological aging links to higher gout risk and increased mortality
Data from NHANES and the UK Biobank show phenotypic and biological age measures track with gout incidence and subsequent survival.Data from NHANES and the UK Biobank show phenotypic and biological age measures track with gout incidence and subsequent survival.
Exercise linked to slower epigenetic aging in breast cancer survivors
In a randomized trial of 124 breast cancer survivors, a 12-month exercise intervention slowed epigenetic aging measured by GrimAge2 and DNAmFitAge…In a randomized trial of 124 breast cancer survivors, a 12-month exercise intervention slowed epigenetic aging measured by GrimAge2 and DNAmFitAge compared to a wellness control.
Telomere attrition marks disease severity in chronic cholestatic liver diseases
Epigenetic telomere length analysis in patients with sclerosing or biliary cholangitis reveals converging markers of accelerated biological aging.Epigenetic telomere length analysis in patients with sclerosing or biliary cholangitis reveals converging markers of accelerated biological aging.
High metabolic inflammation trajectories predict faster frailty progression in older adults
Tracking the combined C-reactive protein-triglyceride-glucose index over time identified older adults at greater risk of incident frailty in two…Tracking the combined C-reactive protein-triglyceride-glucose index over time identified older adults at greater risk of incident frailty in two national cohorts.