Abnormal multisystem blood biomarkers

Abnormal multisystem blood biomarkers are associated with annual increase in disability burden in humans (β = 0.06, 95% CI: 0.02–0.09).

“those with abnormalities in two systems had a significantly faster annual increase in disability burden (β = 0.06, 95% CI: 0.02-0.09)”

HumansAbnormal biomarker values in two biological systems versus normal values across all systems4 years

Abnormal Blood Biomarkers and Cumulative Disability Burden in Middle-Aged and Older Adults: Evidence from Two Nationally Representative Surveys in the United States and China

Journal of cardiovascular development and disease·31 Oct 2025