5-factor SASP model

5-factor SASP model predicts overall survival in humans (5-year OS AUC: 0.90).

“We developed a 5-factor SASP model that demonstrated superior predictive performance for OS compared to chronological age, R-ISS stage, and clinical frailty, and TNF-RI alone (5-year OS AUC: 0.90).”

Humansmultiple myelomaplasma5 years

Biomarkers of Cellular Senescence and their Association with Frailty, Clinical Outcomes, and Survival in Multiple Myeloma

Research square·19 Mar 2026Preprint