[18F]MK6240 tau-PET signal

1. Female sex increases [18F]MK6240 tau-PET signal in humans.

   “We observed higher [ 18 F]MK6240 meningeal signal in females compared to males”

   Humanscognitively unimpaired amyloid-β-meningesfemales

   Impact of sex, age and glymphatic clearance on meningeal tau PET signal

   AAIC 2025 abstract·24 Dec 2025

1. gBOLD/CSF coupling is associated with [18F]MK6240 tau-PET signal in humans.

   “meningeal signal of [ 18 F]MK6240 is significantly associated with glymphatic clearance in females”

   Humanscognitively unimpaired amyloid-β-meningesfemales

   Impact of sex, age and glymphatic clearance on meningeal tau PET signal

   AAIC 2025 abstract·24 Dec 2025

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