[18F]MK6240 meningeal signal

Biomarker

1 paper3 findings

  • Humans1

Associations

3

glymphatic clearance

upin humans1

1 study
  1. glymphatic clearance is associated with [18F]MK6240 meningeal signal in humans.

    “meningeal signal of [ 18 F]MK6240 is significantly associated with glymphatic clearance in females”

    Humanscognitively unimpaired amyloid-beta-negativefemales

    Impact of sex, age and glymphatic clearance on meningeal tau PET signal

    AAIC 2025 abstract23 Dec 2025

Sex

upin humans1

1 study
  1. Sex is associated with [18F]MK6240 meningeal signal in humans.

    “We observed higher [ 18 F]MK6240 meningeal signal in females compared to males while no difference was found for [ 18 F]FTP signal”

    Humanscognitively unimpaired amyloid-beta-negativefemales

    Impact of sex, age and glymphatic clearance on meningeal tau PET signal

    AAIC 2025 abstract23 Dec 2025

[18F]FTP meningeal signal

upin humans1

1 study
  1. [18F]MK6240 meningeal signal is associated with [18F]FTP meningeal signal in humans.

    “[ 18 F]MK6240 and [ 18 F]FTP meningeal signal significantly correlated with each other in both sexes”

    Humanscognitively unimpaired amyloid-beta-negative

    Impact of sex, age and glymphatic clearance on meningeal tau PET signal

    AAIC 2025 abstract23 Dec 2025

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