[18F]FEOBV cholinergic binding

Biomarker

1 paper2 findings

  • Human trial1

Interventions

1

Cognitive training

upin humans1

1 study
  1. Cognitive training increases [18F]FEOBV cholinergic binding in humans.

    “Training significantly increased cholinergic binding in the anterior cingulate, medial prefrontal cortex, insula, and orbitofrontal cortex”

    Human trialhealthy older adults10 weeksn = 92

    Whole-brain cholinergic modulation following computerized cognitive training in healthy older adults: a [18F]FEOBV PET study

    GeroScience27 Aug 2026

More on Cognitive training

Associations

1

Cognitive function

upin humans1

1 study
  1. [18F]FEOBV cholinergic binding is associated with cognitive function in humans.

    “higher baseline cholinergic binding in prefrontal and insular regions was associated with better baseline attentional performance”

    Humanshealthy older adults at baseline

    Whole-brain cholinergic modulation following computerized cognitive training in healthy older adults: a [18F]FEOBV PET study

    GeroScience27 Aug 2026

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