17α-estradiol

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Interventions

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Letrozole

downin rats1

1 study

Letrozole decreases 17α-estradiol in rats.
“injection of the inhibitor into the brain reduced the 17α-estradiol level”
Animalsbrain injection in male ratsbrainmales
17α-estradiol is generated locally in the male rat brain and can regulate GAD65 expression and anxiety
NeuropharmacologyNov 6, 2014

More on Letrozole

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5 papers in 12 months

bioRxivAug 20

17α-Estradiol Confers Limited Protection Against APOE4 Phenotypes in Middle-Aged Female Mice

Preprint: experiments in miceInterventions

GeroScienceJul 22

VCD-induced estropause fails to enhance responsiveness to 17α-estradiol in adult female mice

Experiments in miceInterventions

bioRxivJul 10

Multi-Tissue Metabolomic Signatures of Five Longevity Interventions Converge on Ergothioneine and Lipid Remodeling in Male UM-HET3 Mice

Preprint: experiments in miceInterventions

bioRxivJun 29

Geroprotective interventions preserve trabecular bone during ageing in female mice

Preprint: experiments in miceBones and joints

Ageing Research ReviewsMay 17

17α-Estradiol: A mildly feminizing estrogen with sex-specific metabolic and lifespan benefits

ReviewInterventions

eLifeSep 25

The effects of 17α-estradiol treatment on endocrine system revealed by single-nucleus transcriptomic sequencing of hypothalamus

Experiments in ratsInterventions

eLifeSep 10

The effects of 17α-estradiol treatment on endocrine system revealed by single-nucleus transcriptomic sequencing of hypothalamus

Preprint: experiments in ratsInterventions

Communications MedicineJun 11

Protection against APOE4-associated phenotypes with the longevity-promoting intervention 17α-estradiol in middle-aged male mice

Experiments in miceInterventions

eLifeDec 23

The effects of 17α-estradiol treatment on endocrine system revealed by single-nucleus transcriptomic sequencing of hypothalamus

Preprint: experiments in ratsInterventions

GeroScienceDec 12

Downregulation of the NF-κB protein p65 is a shared phenotype among most anti-aging interventions

Experiments in miceInterventions