From ClinicalTrials.gov

Clinical trials

Trials of drugs and interventions aimed at aging, of age-related conditions through aging biology, and of healthspan itself: new registrations, status changes and first results.

Phase 2Active, not recruitingGeroscience intervention

Nicotinamide Riboside Supplementation for Treating Arterial Stiffness and Elevated Systolic Blood Pressure in Patients With Moderate to Severe CKD

Nicotinamide riboside in Vascular Diseases, Kidney Disease, Blood Pressure

University of Colorado, Denver · 118 planned · NCT04040959 · updated 2 Oct 2026

Phase 2Active, not recruitingGeroscience intervention

Nicotinamide Riboside for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults

Nicotinamide riboside in Hypertension, Aging

Douglas Seals · 118 planned · NCT03821623 · updated 2 Oct 2026

Phase 2CompletedAge-related condition

Study to Determine Optimal Dose and Evaluate Safety, Tolerability, and Pharmacokinetics of Progerinin in Patients With Hutchinson-Gilford Progeria Syndrome (HGPS)

Progerinin, Lonafarnib in Hutchinson-Gilford Progeria Syndrome

PRG Science & Technology Co., Ltd. · 10 enrolled · NCT06775041 · updated 2 Oct 2026

Phase 1/2Not yet recruitingGeroscience intervention

Precision Microbiota Interventions for Senoreduction Trial (PreMIS)

Limosilactobacillus reuteri, Blueberry extract in HIV Infections, Alcohol Drinking, Aging

Louisiana State University Health Sciences Center in New Orleans · 160 planned · NCT07462767 · updated 1 Oct 2026