Papers by Y Yang

400+ results

  1. Research Square

    Loss of a matrix enzyme triggers adult bone loss in mice

    Mice lacking the enzyme MMP14 in bone-forming cells initially gained bone mass when young, but later developed severe bone loss driven by immune cells.Mice lacking the enzyme MMP14 in bone-forming cells initially gained bone mass when young, but later developed severe bone loss driven by immune cells.

    Preprint: experiments in miceBones and joints
  2. Research Square

    Standard lab tests mislabel normal aging in Chinese adults

    In 4,392 healthy Chinese adults, standard medical reference ranges flagged 58.8% of women aged 50 to 59 as having abnormal cholesterol.In 4,392 healthy Chinese adults, standard medical reference ranges flagged 58.8% of women aged 50 to 59 as having abnormal cholesterol.

    Preprint: cross-sectional study of 4,392 peopleBiomarkers
  1. Ecotoxicology and Environmental Safety

    Tributyl phosphate caused signs of liver aging in rats

    An experiment in rats linked the chemical’s effects to fumarate, a substance involved in metabolism, and DNA escaping from cells’ energy-producing structures.An experiment in rats linked the chemical’s effects to fumarate, a substance involved in metabolism, and DNA escaping from cells’ energy-producing structures.

    Experiments in ratsMechanisms
  2. Cardiovascular Diabetology

    Combined blood marker linked to cardiovascular disease risk

    An observational study followed 5,474 Chinese participants from 2011 to 2020 and linked higher marker values to progression to clinical cardiovascular disease.An observational study followed 5,474 Chinese participants from 2011 to 2020 and linked higher marker values to progression to clinical cardiovascular disease.

    Cohort study of 5,474 peopleCardiovascular disease
  3. BMC Medicine

    Carbon dioxide and heatwaves linked to diabetes in China

    Higher carbon dioxide concentrations and more frequent heatwaves were linked to diabetes, with odds ratios—comparisons of diabetes odds—of 1.14 and 1.48, respectively.Higher carbon dioxide concentrations and more frequent heatwaves were linked to diabetes, with odds ratios—comparisons of diabetes odds—of 1.14 and 1.48, respectively.

    Cross-sectional study of 134,403 peopleDiabetes
  4. BMC Geriatrics

    High, rising social stress linked to death risk in older adults

    The adjusted hazard ratio, which compares death rates over time, was 1.10 for consistently high, rising social stress versus initially lower, rising stress.The adjusted hazard ratio, which compares death rates over time, was 1.10 for consistently high, rising social stress versus initially lower, rising stress.

    Cohort study of 10,938 peoplePopulations