Multi-ancestry MHC-pQTL mapping reveals disease-linked HLA protein networks and shared genetic architecture
Research Square
Abstract
The major histocompatibility complex (MHC) is one of the most polymorphic and disease-relevant regions of the human genome, yet the downstream effects of MHC variation on circulating protein networks across ancestries remain incompletely defined.
The paper
Yang Luo, Sarah Sarguroh, Sam Morris, Alexander J. Mentzer
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Esther Ng, Guillaume Butler-Laporte, Ruth Nanjala, Ling Yang, Liming Li, Junshi Chen, pei pei, Jun Lv, Canqing Yu, Dianjianyi Sun, Alfred Pozarickij, Zhengming Chen, Iona Y. Millwood, Robin G. Walters,University of Oxford
Research Square · 21 Sep 2026 · CC BY · Preprint, not peer-reviewed
