InterventionsAnimalsPreprint

Spatial evidence of senescence-associated pathology after myocardial infarction in humans and therapeutic targeting in ageing mice

Research Square

Abstract

Myocardial infarction predominantly affects older adults, yet whether post-injury senolysis improves repair in a middle-aged heart, and whether senescence-associated pathology is present in human post-infarction myocardium, remain unclear.

The paper

Redgrave RE, Zormpas E, Mathison L et al.

Research Square · 8 Sep 2026 · CC BY · Preprint, not peer-reviewed

doi.org/10.21203/rs.3.rs-10930426/v1