Research Square

Development and Temporal Validation of a Nomogram for Predicting Synchronous Brain Metastasis in Clear Cell Renal Cell Carcinoma: A Population-Based Study

Preprint: study in peopleBiomarkers

Abstract

Purpose To develop and temporally validate a pre-treatment nomogram for predicting synchronous brain metastasis (BM) in clear cell renal cell carcinoma (ccRCC), addressing the lack of risk-stratification tools to guide brain MRI screening.

The paper

Beijing Tian Tan Hospital

Research Square, 15 Aug 2026, CC BY, Preprint, not peer-reviewed

doi.org/10.21203/rs.3.rs-10434149/v1