The Journal of Nutrition

Corn and milk proteins similarly boost muscle protein production

Muscle protein production rose 216% from baseline with 20 grams of corn protein, versus 77% with a low-energy placebo without protein.

Figure 1 from The Journal of Nutrition
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Figure 1. Lim et al.
Randomized trial in 48 healthy older adults, against milk proteinInterventions

Double-blind, placebo-controlled, registered NCT05917223

Limit: Only 48 healthy older adults were included

Stake: An author holds patents licensed to Exerkine.

Edited by Boris Djordjevic · AgingResearch.News

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A randomized, double-blind, placebo-controlled trial studied 48 healthy older adults whose average age was 68. The participants included 24 men and 24 women. They consumed 20 grams of corn protein, a pea-and-corn protein blend or milk protein, or received a low-energy placebo without protein. Each participant also performed three sets of 10 knee extensions with one leg. Researchers collected blood and muscle samples to measure muscle protein production.

All three protein options increased muscle protein production more than the placebo. The researchers found no differences between the protein groups. Resistance exercise further increased muscle protein production compared with supplementation alone in every group.

Why it matters

Older adults have a reduced muscle-building response to protein. The trial addressed whether protein source matters for stimulating production of new muscle proteins in later life.

Caveats

The measured outcome was muscle protein production, which does not establish lasting gains in muscle size or strength. The trial included only 48 healthy older adults.